Plague is an illness you get from Yersinia pestis bacterium. You usually get the most common form (bubonic plague) from flea bites, but you can get pneumonic plague from someone who’s infected. Plague caused deadly pandemics in the past and still exists in many countries today. You can survive plague if you’re treated with antibiotics quickly. Plague - Bubonic, Pneumonic, Septicaemic: Plague is an ancient disease that was described during Classical times as occurring in North Africa and the Middle East. It is sometimes presumed to be the disease behind several historic epidemics, such as the pestilence described as striking the Philistines in the biblical book of 1 Samuel.“[Blurbs] are a PLAGUE on this industry” said Lucy Carson (emphasis her own), a literary agent at The Friedrich Agency who has worked with literary bigwigs like Pulitzer Prize-winner Elizabeth ...Wright — a staff writer at The New Yorker, where the article that “The Plague Year” is based on first appeared — has performed a virtuoso feat and given us a book of panoramic breadth. It ...The Crossword Solver found 60 answers to "plague", 4 letters crossword clue. The Crossword Solver finds answers to classic crosswords and cryptic crossword puzzles. Enter the length or pattern for better results. Click the answer to find similar crossword clues . Enter a Crossword Clue.Evidence suggests Washtenaw County’s criminal legal system is rife with disparities based on race, and those are among the 65 recommendations of a sprawling new report released on Aug. 31 that ...Responding to a Plague Bioterrorism Event. Kettles, buckets, lanterns, and other equipment were used in catching rats during the Public Health Service campaign against the New Orleans plague epidemic of 1914-1920. (Library of Medicine) Page last reviewed: February 7, 2022. Content source: Centers for Disease Control and Prevention, National ...The Plague Disease and Plague as a Bioweapon sections of this Safety and Health Topic provide extensive information on the hazards associated with plague and applicable controls. Additional guidance specific to various types of workers, and associated issues on recognizing and controlling exposure to plague is provided in the following sections ... Plague is an illness you get from Yersinia pestis bacterium. You usually get the most common form (bubonic plague) from flea bites, but you can get pneumonic plague from someone who’s infected. Plague caused deadly pandemics in the past and still exists in many countries today. You can survive plague if you’re treated with antibiotics quickly.How to pronounce plague. How to say plague. Listen to the audio pronunciation in the Cambridge English Dictionary. Learn more. Bubonic plague is one of three types of plague caused by the bacterium Yersinia pestis. [1] One to seven days after exposure to the bacteria, flu-like symptoms develop. [1] These symptoms include fever, headaches, and vomiting, [1] as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered the skin. [2] Treatment for plague begins as soon as the health care provider suspects the disease. Treatment is typically done in the hospital. Antibiotics that may be used include the following: Gentamicin. Doxycycline (Monodox, Vibramycin, others). Ciprofloxacin (Cipro). Levofloxacin. Moxifloxacin (Avelox). Chloramphenicol.Black Death. The Black Death (also known as the Pestilence, the Great Mortality or the Plague) [a] was a bubonic plague pandemic occurring in Western Eurasia and North Africa from 1346 to 1353. It is the most fatal pandemic recorded in human history, causing the deaths of 75–200 million people, [1] peaking in Europe from 1347 to 1351.Apr 16, 2020 · The Black Death of 1347-1352 CE is the most infamous plague outbreak of the medieval world, unprecedented and unequaled until the 1918-1919 CE flu pandemic in the modern age. The cause of the plague was unknown and, in accordance with the general understanding of the Middle Ages, was attributed to supernatural forces and, primarily, the will or ... Plague definition, an epidemic disease that causes high mortality; pestilence. See more. Plague is an illness you get from Yersinia pestis bacterium. You usually get the most common form (bubonic plague) from flea bites, but you can get pneumonic plague from someone who’s infected. Plague caused deadly pandemics in the past and still exists in many countries today. You can survive plague if you’re treated with antibiotics quickly. a serious disease that kills many people, often used to refer to bubonic plague, a very infectious disease caused by bacteria spread mainly by fleas (= small insects that bite) on rats or other animals, that causes swelling, fever, and usually death in humans:Florida Health. Disease Control. [email protected]. 850-245-4444. Florida Health. 4052 Bald Cypress Way. Tallahassee, FL 32399. Plague is an acute, bacterial disease caused by Yersinia pestis, a Gram-negative bacteria that is transmitted from rodent to rodent by infected fleas.The 10-year-old child who died of plague earlier this month was a La Plata County resident. Plague is caused by bacteria and usually is transmitted by bites from infected fleas. Prairie dogs ...History of Plague Epidemics. The plague has afflicted humanity for thousands of years.1, 2, 3 Molecular studies identified the presence of the Y. pestis plague DNA genome in 2 Bronze Age skeletons dated at roughly 3800 years old. 9 In the biblical book 1 Samuel from approximately 1000 BCE, the Philistines experience an outbreak of tumors associated with rodents, which might have been bubonic ...The plague is treatable in humans and animals if caught and addressed early. CBSN Denver noted that last year, two people in Colorado were confirmed to have contracted the plague, and both survived.Plague doctors, or at least images of plague doctors, are having a bit of a cultural moment again, roughly 300 years after their actual heyday. Subscribe to newsletters Subscribe for $39.99/yearThe plague hits Marseille, Paris and Normandy, and then the strain splits, with one strain moving onto the now-Belgian city of Tournai to the east and the other passing through Calais. and Avignon ...Plague is an illness you get from Yersinia pestis bacterium. You usually get the most common form (bubonic plague) from flea bites, but you can get pneumonic plague from someone who’s infected. Plague caused deadly pandemics in the past and still exists in many countries today. You can survive plague if you’re treated with antibiotics quickly. Plague is endemic in Madagascar and outbreaks occur regularly, although every outbreak is cause for concern. Furthermore, pneumonic plague is a notifiable disease under the International Health Regulations 2005. By the following day, 30 August, 25 suspected cases of pneumonic plague had been notified to the health authorities from Arivonimamo ...Background. There are three types of plague. Most of the sick in 1665-1666 had bubonic plague. This created swellings (buboes) in the lymph nodes found in the armpits, groin and neck. Plague sufferers experienced headaches, vomiting and fever. They had a 30% chance of dying within two weeks.Collection. by Mark Cartwright. published on 26 March 2020. Plagues have swept through humanity ever since communities have gathered together in concentrated groups. In this collection of resources, we look at just some of the pandemics that raged throughout Antiquity and the Middle Ages, from the plague that ripped through Athens in the 5th ...Plague is an infectious disease caused by the bacteria Yersinia pestis, a zoonotic bacteria, usually found in small mammals and their fleas. It is transmitted between animals from their fleas. Humans can be contaminated by the bite of infected fleas, through direct contact with infected materials or by inhalation.Plague is an infectious disease caused by the bacterium Yersinia pestis. Symptoms include fever, weakness and headache. Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms. Plague - Bubonic, Pneumonic, Septicaemic: Plague is an ancient disease that was described during Classical times as occurring in North Africa and the Middle East. It is sometimes presumed to be the disease behind several historic epidemics, such as the pestilence described as striking the Philistines in the biblical book of 1 Samuel.Apr 16, 2020 · The Black Death of 1347-1352 CE is the most infamous plague outbreak of the medieval world, unprecedented and unequaled until the 1918-1919 CE flu pandemic in the modern age. The cause of the plague was unknown and, in accordance with the general understanding of the Middle Ages, was attributed to supernatural forces and, primarily, the will or ... Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation with over 700 million games played! Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.Oct 29, 2020 · Plague is a serious infectious disease that affects mammals, including humans. It can spread through animal or human contact. The bacteria that cause plague live in many parts of the world ... Plague is a febrile illness that typically manifests into one or more clinical syndromes, often reflecting the route of exposure to the bacterium. These clinical syndromes include bubonic, septicemic, and pneumonic plague. Several classes of antibiotics are effective against plague. Plague can be rapidly fatal if appropriate antimicrobial ...Pneumonic plague is the most serious form of the disease and the only form that can spread from person to person. As a result of a bioterrorist attack, sick people would likely be seen outside the areas where plague naturally occurs due to the potential for release in other areas and person-to-person spread between close contacts. Mar 12, 2020 · In the 17th century, people believed these outfits could purify poisonous air. They were wrong. During the 17th-century European plague, physicians wore beaked masks, leather gloves, and long ... Plague definition, an epidemic disease that causes high mortality; pestilence. See more. “[Blurbs] are a PLAGUE on this industry” said Lucy Carson (emphasis her own), a literary agent at The Friedrich Agency who has worked with literary bigwigs like Pulitzer Prize-winner Elizabeth ...Nov 26, 2019 · Plague is a plausible diagnosis for people who are sick and live in, or have recently traveled to, the western United States or any other plague-endemic area. The most common sign of bubonic plague is the rapid development of a swollen and painful lymph gland called a bubo. A known flea bite or the presence of a bubo may help a doctor to ... What is plague? Plague is a disease caused by Yersinia pestis that affects rodents (e.g., squirrels, prairie dogs, or mice), other mammals (e.g., rabbits or hares), and humans. These bacteria are found in many areas of the world, including the western United States. There are three forms of plague: bubonic (lymph node infection), pneumonic (lung […]Bubonic plague: Humans can come into contact with plague when an infected flea bites a person or when materials that have plague bacteria enter through a break (a cut or sore) in a person's skin. This is the most common form of plague. Pneumonic plague: Humans can come into contact with plague when a person breathes in plague bacteria from the air.Oct 29, 2020 · Plague is a serious infectious disease that affects mammals, including humans. It can spread through animal or human contact. The bacteria that cause plague live in many parts of the world ... People infected with plague usually develop influenza-like symptoms after an incubation period of 3–7 days. Symptoms include fever, chills, aches, weakness, vomiting and nausea. There are 3 main forms of plague. Bubonic plague is the most common and is caused by the bite of an infected flea.The Black Death was a bubonic plague pandemic, which reached England in June 1348. It was the first and most severe manifestation of the second pandemic, caused by Yersinia pestis bacteria. The term Black Death was not used until the late 17th century. Originating in Asia, it spread west along the trade routes across Europe and arrived on the ...Wright — a staff writer at The New Yorker, where the article that “The Plague Year” is based on first appeared — has performed a virtuoso feat and given us a book of panoramic breadth. It ...What is plague? Plague is a disease caused by Yersinia pestis that affects rodents (e.g., squirrels, prairie dogs, or mice), other mammals (e.g., rabbits or hares), and humans. These bacteria are found in many areas of the world, including the western United States. There are three forms of plague: bubonic (lymph node infection), pneumonic (lung […]What is plague? Plague is a disease caused by Yersinia pestis that affects rodents (e.g., squirrels, prairie dogs, or mice), other mammals (e.g., rabbits or hares), and humans. These bacteria are found in many areas of the world, including the western United States. There are three forms of plague: bubonic (lymph node infection), pneumonic (lung […] Oct 12, 2016 · The plague laid siege to the city of London several times during the 16th and 17th centuries, most famously between 1665 and 1666. The pestilence first arose in the suburb of St. Giles-in-the ... Apr 7, 2020 · Experts believe that the name “Black Plague” was a mistranslation of the Latin word “atra mors” which could mean either “terrible” or “black.”. It was originally estimated that on average, a third of the population of affected areas was wiped out by the plague over its most destructive decade between 1346 and 1353, but other ... Black Death. The Black Death (also known as the Pestilence, the Great Mortality or the Plague) [a] was a bubonic plague pandemic occurring in Western Eurasia and North Africa from 1346 to 1353. It is the most fatal pandemic recorded in human history, causing the deaths of 75–200 million people, [1] peaking in Europe from 1347 to 1351.Collection. by Mark Cartwright. published on 26 March 2020. Plagues have swept through humanity ever since communities have gathered together in concentrated groups. In this collection of resources, we look at just some of the pandemics that raged throughout Antiquity and the Middle Ages, from the plague that ripped through Athens in the 5th ...Experts believe that the name “Black Plague” was a mistranslation of the Latin word “atra mors” which could mean either “terrible” or “black.”. It was originally estimated that on average, a third of the population of affected areas was wiped out by the plague over its most destructive decade between 1346 and 1353, but other ...May 18, 2023 · Plague. Plague, caused by the bacterium Yersinia pestis, is a disease that affects humans and other mammals. People typically get infected after being bitten by a rodent flea that is carrying the bacterium or by handling a plague-infected animal. Although the disease killed millions in Europe during the Middle Ages, antibiotics effectively ... This plague struck the earth, mainly Europe and Asia, from around 1346 to 1353. The plague killed between 75 and 200 million people. The cause of the plague was a bacterium called Yersinia pestis ...In a plague emergency, CDC and other federal agencies would work closely with state and local partners to coordinate a response. CDC and other federal agencies would respond by: Coordinating activities through the Emergency Operations Center. Communicating information about plague to the public. Providing guidance to healthcare providers ... The Black Death was a devastating global epidemic of bubonic plague that struck Europe and Asia in the mid-1300s. Explore the facts of the plague, the symptoms it caused and how millions died...Plague doctors, or at least images of plague doctors, are having a bit of a cultural moment again, roughly 300 years after their actual heyday. Subscribe to newsletters Subscribe for $39.99/yearplague definition: 1. to cause worry, pain, or difficulty to someone or something over a period of time: 2. to annoy…. Learn more. Bubonic plague is one of three types of plague caused by the bacterium Yersinia pestis. [1] One to seven days after exposure to the bacteria, flu-like symptoms develop. [1] These symptoms include fever, headaches, and vomiting, [1] as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered the skin. [2] There are three kinds of Plague disease: Bubonic plague disease – It is an infection in the lymph nodes of the body. The lymph nodes swell and cause serious pain and it is transmitted through the fleas that contain the bacteria. Pneumonic plague disease – It is a contagious disease that causes infection in the lungs.Plagues of Egypt. Scenes from the book of Exodus: The death of the firstborns (including the Pharaoh 's son), and the Israelites leaving Egypt ( Haggadah shel Pesaḥ, 1325–1374 CE, Barcelona via British Library) The Plagues of Egypt, in the account of the book of Exodus, are ten disasters inflicted on Biblical Egypt by the God of Israel in ... The bubonic plague was the most commonly seen form during the Black Death, with a mortality rate of 30-75% and symptoms including fever of 38 - 41 °C (101-105 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Of those who contracted the bubonic plague, 4 out of 5 died within eight days.Plague is endemic in Madagascar and outbreaks occur regularly, although every outbreak is cause for concern. Furthermore, pneumonic plague is a notifiable disease under the International Health Regulations 2005. By the following day, 30 August, 25 suspected cases of pneumonic plague had been notified to the health authorities from Arivonimamo ...Apr 16, 2020 · The Black Death of 1347-1352 CE is the most infamous plague outbreak of the medieval world, unprecedented and unequaled until the 1918-1919 CE flu pandemic in the modern age. The cause of the plague was unknown and, in accordance with the general understanding of the Middle Ages, was attributed to supernatural forces and, primarily, the will or ... Nov 16, 2022 · Over 80% of United States plague cases have been the bubonic form. In recent decades, an average of seven human plague cases have been reported each year (range: 1–17 cases per year). Plague has occurred in people of all ages (infants up to age 96), though 50% of cases occur in people ages 12–45. It occurs in both men and women, though ... “[Blurbs] are a PLAGUE on this industry” said Lucy Carson (emphasis her own), a literary agent at The Friedrich Agency who has worked with literary bigwigs like Pulitzer Prize-winner Elizabeth ...Nov 26, 2019 · Plague is a plausible diagnosis for people who are sick and live in, or have recently traveled to, the western United States or any other plague-endemic area. The most common sign of bubonic plague is the rapid development of a swollen and painful lymph gland called a bubo. A known flea bite or the presence of a bubo may help a doctor to ... Treatment for plague begins as soon as the health care provider suspects the disease. Treatment is typically done in the hospital. Antibiotics that may be used include the following: Gentamicin. Doxycycline (Monodox, Vibramycin, others). Ciprofloxacin (Cipro). Levofloxacin. Moxifloxacin (Avelox). Chloramphenicol.Oct 29, 2020 · Plague is a serious infectious disease that affects mammals, including humans. It can spread through animal or human contact. The bacteria that cause plague live in many parts of the world ... Oct 12, 2016 · The plague laid siege to the city of London several times during the 16th and 17th centuries, most famously between 1665 and 1666. The pestilence first arose in the suburb of St. Giles-in-the ... plague meaning: 1. to cause worry, pain, or difficulty to someone or something over a period of time: 2. to annoy…. Learn more.The Justinian Plague of 541-544 . The first great pandemic of bubonic plague where people were recorded as suffering from the characteristic buboes and septicaemia was the Justinian Plague of 541 CE, named after Justinian I, the Roman emperor of the Byzantine Empire at the time. The epidemic originated in Ethiopia in Africa and spread to ...History of Plague Epidemics. The plague has afflicted humanity for thousands of years.1, 2, 3 Molecular studies identified the presence of the Y. pestis plague DNA genome in 2 Bronze Age skeletons dated at roughly 3800 years old. 9 In the biblical book 1 Samuel from approximately 1000 BCE, the Philistines experience an outbreak of tumors associated with rodents, which might have been bubonic ...What is plague? Plague is a disease caused by Yersinia pestis that affects rodents (e.g., squirrels, prairie dogs, or mice), other mammals (e.g., rabbits or hares), and humans. These bacteria are found in many areas of the world, including the western United States. There are three forms of plague: bubonic (lymph node infection), pneumonic (lung […] Plague is an infectious disease caused by the bacteria Yersinia pestis, a zoonotic bacteria, usually found in small mammals and their fleas. It is transmitted between animals from their fleas. Humans can be contaminated by the bite of infected fleas, through direct contact with infected materials or by inhalation.Define plague. plague synonyms, plague pronunciation, plague translation, English dictionary definition of plague. ) n. 1. a. A highly infectious epidemic disease ... In a plague emergency, CDC and other federal agencies would work closely with state and local partners to coordinate a response. CDC and other federal agencies would respond by: Coordinating activities through the Emergency Operations Center. Communicating information about plague to the public. Providing guidance to healthcare providers ...History of Plague Epidemics. The plague has afflicted humanity for thousands of years.1, 2, 3 Molecular studies identified the presence of the Y. pestis plague DNA genome in 2 Bronze Age skeletons dated at roughly 3800 years old. 9 In the biblical book 1 Samuel from approximately 1000 BCE, the Philistines experience an outbreak of tumors associated with rodents, which might have been bubonic ...The Justinian Plague of 541-544 . The first great pandemic of bubonic plague where people were recorded as suffering from the characteristic buboes and septicaemia was the Justinian Plague of 541 CE, named after Justinian I, the Roman emperor of the Byzantine Empire at the time. The epidemic originated in Ethiopia in Africa and spread to ...Plague, infectious disease caused by Yersinia pestis, a bacterium transmitted from rodents to humans by the bite of infected fleas. Plague has caused some of the most-devastating epidemics in history. It was the disease behind the Black Death of the 14th century, when as much as one-third of Europe’s population died.Jul 23, 2021 · The plague is treatable in humans and animals if caught and addressed early. CBSN Denver noted that last year, two people in Colorado were confirmed to have contracted the plague, and both survived. a serious disease that kills many people, often used to refer to bubonic plague, a very infectious disease caused by bacteria spread mainly by fleas (= small insects that bite) on rats or other animals, that causes swelling, fever, and usually death in humans:The plague is treatable in humans and animals if caught and addressed early. CBSN Denver noted that last year, two people in Colorado were confirmed to have contracted the plague, and both survived.plague n. (infestation of insects or rats) invasion nf. (de moustiques, sauterelles,...) nuée nf. The citizens of Hamlin called on the services of the Pied Piper because of a plague of rats. Les citoyens de la ville de Hamelin ont fait appel au service du joueur de flûte à cause d'une invasion de rats. plague n. Plague - Bubonic, Pneumonic, Septicaemic: Plague is an ancient disease that was described during Classical times as occurring in North Africa and the Middle East. It is sometimes presumed to be the disease behind several historic epidemics, such as the pestilence described as striking the Philistines in the biblical book of 1 Samuel.Background. There are three types of plague. Most of the sick in 1665-1666 had bubonic plague. This created swellings (buboes) in the lymph nodes found in the armpits, groin and neck. Plague sufferers experienced headaches, vomiting and fever. They had a 30% chance of dying within two weeks.What is plague? Plague is a disease caused by Yersinia pestis that affects rodents (e.g., squirrels, prairie dogs, or mice), other mammals (e.g., rabbits or hares), and humans. These bacteria are found in many areas of the world, including the western United States. There are three forms of plague: bubonic (lymph node infection), pneumonic (lung […] Define plague. plague synonyms, plague pronunciation, plague translation, English dictionary definition of plague. ) n. 1. a. A highly infectious epidemic disease ... The Black Death was a devastating global epidemic of bubonic plague that struck Europe and Asia in the mid-1300s. Explore the facts of the plague, the symptoms it caused and how millions died...The Plague Disease and Plague as a Bioweapon sections of this Safety and Health Topic provide extensive information on the hazards associated with plague and applicable controls. Additional guidance specific to various types of workers, and associated issues on recognizing and controlling exposure to plague is provided in the following sections ... Responding to a Plague Bioterrorism Event. Kettles, buckets, lanterns, and other equipment were used in catching rats during the Public Health Service campaign against the New Orleans plague epidemic of 1914-1920. (Library of Medicine) Page last reviewed: February 7, 2022. Content source: Centers for Disease Control and Prevention, National ...
Plague was present in at least one location in the Islamic world virtually every year between 1500 and 1850. [56] Plague repeatedly struck the cities of North Africa. Algiers lost 30,000–50,000 to it in 1620–1621, and again in 1654–1657, 1665, 1691, and 1740–1742. [57] . Rn to msn
Aug 23, 2023 · Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Brilliantly executed with innovative gameplay and built ... Mar 26, 2020 · Collection. by Mark Cartwright. published on 26 March 2020. Plagues have swept through humanity ever since communities have gathered together in concentrated groups. In this collection of resources, we look at just some of the pandemics that raged throughout Antiquity and the Middle Ages, from the plague that ripped through Athens in the 5th ... Nov 22, 2021 · The Moscow Plague. The Moscow plague hit the earth in 1770. It mainly impacted the Moscow people. And, it was believed to be a replication of the bubonic plague. The plague killed an average of 50 ... How to pronounce plague. How to say plague. Listen to the audio pronunciation in the Cambridge English Dictionary. Learn more. plague翻译：不斷困擾;折磨;使受煎熬, （尤指因不停提問而）使煩惱，打攪, 瘟疫。了解更多。Bubonic plague is one of three types of plague caused by the bacterium Yersinia pestis. [1] One to seven days after exposure to the bacteria, flu-like symptoms develop. [1] These symptoms include fever, headaches, and vomiting, [1] as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered the skin. [2]Plague is an infectious disease caused by the bacterium Yersinia pestis. Symptoms include fever, weakness and headache. Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms.Oct 12, 2016 · The plague laid siege to the city of London several times during the 16th and 17th centuries, most famously between 1665 and 1666. The pestilence first arose in the suburb of St. Giles-in-the ... The Plague Runeword is a Weapon Runeword in Diablo II: Resurrected Patch 2.7 & Ladder Season 4, introduced in the Patch 2.4 Ladder Season 1. In this guide, we will give you quick facts about Plague, strengths and weaknesses, best classes and specs, best Mercenary use, best socketed base items to use to create this Runeword, and hints for farming the necessary Runes.Treatment for plague begins as soon as the health care provider suspects the disease. Treatment is typically done in the hospital. Antibiotics that may be used include the following: Gentamicin. Doxycycline (Monodox, Vibramycin, others). Ciprofloxacin (Cipro). Levofloxacin. Moxifloxacin (Avelox). Chloramphenicol.Plague is a serious illness caused by a germ called Yersinia pestis. The germs mostly live in small rodents and their fleas. The most common way for humans to get plague is a flea bite. Plague is a rare disease. The illness mostly occurs in only a few countries around the world.plague meaning: 1. to cause worry, pain, or difficulty to someone or something over a period of time: 2. to annoy…. Learn more. .
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